Support the Work

If you have found the information on this blog useful, enjoyable, candid, or inspirational ... help keep it reader supported, journalistically driven, available to all, and advertiser-free. If you are able and inspired to do so, please consider a subscription to this blog. You can drop a dime or two every month, every year, or whenever you feel moved.

It will keep me writing, gathering facts, and interviewing the experts.




Parent / Sponsor



Join The Email List

Get Tastiness to Your Inbox

* indicates required

HAVE A QUESTION? > Proline in gluten vs. broth

I have read that proline cannot be broken down in gluten because we do not have the enzymes to break it down, and therefore that is causing damage to our gut. Then, I also read that proline- rich broth is gut healing. Are we talking about two different things?
December 14, 2013 | Unregistered CommenterInpired RN
That is a great question,Inspired RN and it is a confusing concept. I will work to get a MUCH better answer for you (hoping I can get it directly from Dr. Fasano), but my understanding is that it is the form it takes and how it is binding - like glutamine, which is another amino acid gut healer, which is different than the gluten. Here are a few articles that discuss this.

The interview that is being quoted:

A description of amino acids:

A description of glutamine from the University of Maryland Medical School (did not find one for proline):

Main chain hydrogen bond interactions in the binding of proline-rich gluten peptides to the celiac disease-associated HLA-DQ2 molecule.: